GW-406381 (Synonyms: GW406381X) |
| カタログ番号GC36200 |
高度に選択的なシクロオキシゲナーゼ-2 (COX-2) 阻害剤である GW406381 は、慢性収縮損傷後のラットの腓腹神経における自発的な異所性放電を軽減します 。
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Cas No.: 221148-46-5
Sample solution is provided at 25 µL, 10mM.
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GW406381, a highly selective cyclooxygenase-2 (COX-2) inhibitor, attenuates spontaneous ectopic discharge in sural nerves of rats following chronic constriction injury[1][2]. COX-2
[1]. Zhao FY, et al. GW406381, a novel COX-2 inhibitor, attenuates spontaneous ectopic discharge in sural nerves of rats following chronic constriction injury. Pain. 2007 Mar;128(1-2):78-87. [2]. Boswell DJ, et al. Evaluation of GW406381 for treatment of osteoarthritis of the knee: two randomized, controlled studies. Medscape J Med. 2008;10(11):259.
Average Rating: 5 (Based on Reviews and 22 reference(s) in Google Scholar.)
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