13,14-dihydro-15-keto Prostaglandin A2 MaxSpec® Standard

Prostaglandin E2 is metabolized rapidly to 13,14-dihydro-15-keto PGE2 , which is present in the plasma of humans and other mammals. 13,14-dihydro-15-keto PGA2 results from the non-enzymatic dehydration of 13,14-dihydro-15-keto PGE2, a process which is accelerated by the presence of albumin. Further decomposition of 13,14-dihydro-15-keto PGA2 by the intentional addition of base produces bicyclo PGE2 , a stable marker of PGE2 biosynthesis.13,14-dihydro-15-keto PGA2 MaxSpec® standard is a quantitative grade standard of 13,14-dihydro-15-keto PGA2 that has been prepared specifically for mass spectrometry or any application where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This 13,14-dihydro-15-keto PGA2 MaxSpec® standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batchspecificcertificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.