3'-Hydroxy Repaglinide |
| Catalog No.GC39611 |
3'-Hydroxy Repaglinide는 Repaglinide의 주요 CYP2C8 대사 산물입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 874908-14-2
Sample solution is provided at 25 µL, 10mM.
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3'-Hydroxy Repaglinide is a main CYP2C8 metabolite of Repaglinide. Repaglinide is a carbamoylmethyl benzoic acid (CMBA) derivative, which recently has become available for the treatment of type II diabetes[1][2].
[1]. A liquid chromatography-tandem mass spectrometry analysis of nine cytochrome P450 probedrugs and their corresponding metabolites in human serum and urine. Anal Bioanal Chem. 2017 Jan;409(1):251-268. [2]. Honkalammi J, et al. Mechanism-based inactivation of CYP2C8 by gemfibrozil occurs rapidly in humans. Clin Pharmacol Ther. 2011 Apr;89(4):579-86.
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