Ac-ANW-AMC (Synonyms: Ac-Ala-Asn-Trp-AMC) |
| Catalog No.GC42685 |
Ac-ANW-AMC는 면역프로테아좀에 대한 형광 기질입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2357123-49-8
Sample solution is provided at 25 µL, 10mM.
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Ac-ANW-AMC is a fluorogenic substrate for the β5i/LMP7 subunit of the 20S immunoproteasome. [1] Upon cleavage, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify the activity of the β5i/LMP7 subunit of the 20S immunoproteasome. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.
Reference
[1]. Winter, M.B., La Greca, F., Arastu-Kapur, S., et al. Immunoproteasome functions explained by divergence in cleavage specificity and regulation. eLife 6:e27364, (2017).
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