>>Signaling Pathways>> Apoptosis>> Other Apoptosis>>AKOS-22

AKOS-22

Catalog No.GC39620

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AKOS-22 Chemical Structure

Cas No.: 878983-38-1

Size 가격 재고 수량
5mg
US$357.00
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10mg
US$510.00
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25mg
US$881.00
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100mg
US$2,271.00
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

AKOS-22 is a potent mitochondrial protein VDAC1 (voltage-dependent anion channel 1) inhibitor (Kd=15.4 μM). AKOS-22 interacts with VDAC1 and inhibiting both VDAC1 oligomerization and apoptosis. AKOS-22 protects against mitochondrial dysfunction[1].

[1]. Ben-Hail D, et al. Novel Compounds Targeting the Mitochondrial Protein VDAC1 Inhibit Apoptosis and Protectagainst Mitochondrial Dysfunction. Biol Chem. 2016 Nov 25;291(48):24986-25003.

리뷰

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Average Rating: 5 ★★★★★ (Based on Reviews and 32 reference(s) in Google Scholar.)

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