BACE1-IN-1 |
Catalog No.GC31158 |
BACE1-IN-1은 인간 BACE1 및 BACE2에 대해 IC50이 각각 32 및 47nM인 강력하고 고도로 뇌 침투성인 BACE1 억제제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1310347-50-2
Sample solution is provided at 25 µL, 10mM.
BACE1-IN-1 is a potent and highly brain penetrant BACE1 inhibitor with IC50s of 32 and 47 nM for human BACE1 and BACE2, respectively.
[1]. Hilpert H, et al. β-Secretase (BACE1) inhibitors with high in vivo efficacy suitable for clinical evaluation in Alzheimer's disease. J Med Chem. 2013 May 23;56(10):3980-95.
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