>>Signaling Pathways>> Neuroscience>> Beta-secretase>>BACE1-IN-1

BACE1-IN-1

Catalog No.GC31158

BACE1-IN-1은 인간 BACE1 및 BACE2에 대해 IC50이 각각 32 및 47nM인 강력하고 고도로 뇌 침투성인 BACE1 억제제입니다.

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BACE1-IN-1 Chemical Structure

Cas No.: 1310347-50-2

Size 가격 재고 수량
1mg
US$281.00
재고 있음
5mg
US$450.00
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10mg
US$720.00
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

BACE1-IN-1 is a potent and highly brain penetrant BACE1 inhibitor with IC50s of 32 and 47 nM for human BACE1 and BACE2, respectively.

[1]. Hilpert H, et al. β-Secretase (BACE1) inhibitors with high in vivo efficacy suitable for clinical evaluation in Alzheimer's disease. J Med Chem. 2013 May 23;56(10):3980-95.

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