BNP-45 rat (Brain natriuretic peptide-45 rat) |
| Catalog No.GC32612 |
BNP-45 쥐(Brain natriuretic peptide-45 rat)(BNP-45, 쥐)는 강력한 저혈압 및 나트륨 이뇨 효능을 가진 쥐 심장에서 분리된 순환 형태의 쥐 뇌 나트륨 이뇨 펩티드입니다.
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Cas No.: 123337-89-3
Sample solution is provided at 25 µL, 10mM.
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BNP-45 (rat), a 45-amino acid brain natriurctic peptide isolated from rat heart, is a circulating hormone, with natriuretic andhypotensive activities.
BNP-45 (rat), a 45-amino acid brain natriurctic peptide isolated from rat heart, is a circulating hormone, with natriuretic andhypotensive activities[1].
BNP-45 (rat) (0.1, O.2, 0.5, 1.0 and 2.0 nmol/kg, i.v.) shows potent natriuretic and hypotensive activities in anesthetized spontaneously hypertensive rats (SHR) and Wistar-Kyoto rats (WKY). BNP-45 (rat) with high concentration decreases blood pressure in SHR. But WKY is more susceptible than SHR to BNP-45 for diuresis, natriuresis and urinary cGMP excretion. In addition, high dose of BNP-45 (rat) cuases prolonged lowering of blood pressure and urinary cGMP excretion in WKY[1].
[1]. Kita T, et al. Effects of brain natriuretic peptide-45, a circulating form of rat brain natriuretic peptide, in spontaneously hypertensive rats. Eur J Pharmacol. 1991 Sep 4;202(1):73-9.
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