C12 Ceramide (d18:1/12:0) (Synonyms: Cer(d18:1/12:0), C12 Ceramide, Ceramide (d18:1/12:0), N-Lauroyl-D-erythro-Sphingosine) |
| Catalog No.GC43006 |
C12 세라마이드(d18:1/12:0)(N-Lauroyl-D-erythro-sphingosine)는 천연 세라마이드로 C12 스핑고미엘린의 가수분해에 의해 형성됩니다.
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Cas No.: 74713-60-3
Sample solution is provided at 25 µL, 10mM.
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C12 ceramide is a naturally occurring ceramide that is formed when C12 sphingomyelin is hydrolyzed by acid sphingomyelinase (ASM). It is a substrate for acid ceramidase, an enzyme that has 2- to 12-fold higher activity in fibroblasts from patients with Farber disease, a lipid storage disorder. C12 ceramide is found in the Wharton's jelly, a protective coating that surrounds umbilical cord vessels, of babies born to women with pre-eclampsia. BODIPY C12 ceramide has been used to assess levels of ASM activity in plasma of patients with type A or B Niemann-Pick disease.
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