C8 Galactosylceramide (d18:1/8:0) (Synonyms: Galactosylceramide (d18:1/8:0), N-octanoyl-βD-Galactosylceramide, GalCer(d18:1/8:0)) |
Catalog No.GC43110 |
C8 Galactosylceramide is a synthetic C8 short-chain derivative of known membrane microdomain-forming sphingolipids.
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Cas No.: 41613-16-5
Sample solution is provided at 25 µL, 10mM.
C8 Galactosylceramide is a synthetic C8 short-chain derivative of known membrane microdomain-forming sphingolipids. It increases the amount delivered and toxicity of doxorubicin in cancerous but not non-cancerous cells when incorporated into the nanoliposomal membrane of nanoliposomal-doxorubicin. C8 Galactosylceramide induces proliferation and cytokine production by splenocytes in vitro at concentrations ranging from 100-1,000 ng/ml but has no effect on natural killer T cell production in vivo. It also activates NF-κB production in C6 glioma cells when used at a concentration of 10 μM.
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