CIL62 |
Catalog No.GC60707 |
CIL62는 caspase-3/7에 독립적인 세포 사멸 유도제입니다. CIL62의 작용 기전은 Necrostatin-1 의존성 세포 사멸입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 117593-36-9
Sample solution is provided at 25 µL, 10mM.
CIL62 is a caspase-3/7-independent cell death inducer. The mechanism of action of CIL62 is Necrostatin-1 dependent cell death[1].
19 µM (5 µg/mL) Necrostatin-1 suppresses CIL62, but CIL62 is not suppressed by the ferroptosis inducers (antioxidants or iron-chelators)[1].
[1]. Kenichi Shimada, et al. Global Survey of Cell Death Mechanisms Reveals Metabolic Regulation of Ferroptosis. Nat Chem Biol. 2016 Jul;12(7):497-503.
Average Rating: 5
(Based on Reviews and 15 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *