N-Methylisatoic anhydride |
| Catalog No.GC38314 |
N-Methylisatoic anhydride(NMIA)는 RNA의 2'-OH 선택적 아실화제로 SHAPE(Selective 2'-Hydroxyl Acylation Analyzed by Primer Extension) 기술을 사용하여 이차 RNA 구조를 해결하는 데 널리 사용됩니다.
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Cas No.: 10328-92-4
Sample solution is provided at 25 µL, 10mM.
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N-Methylisatoic anhydride (NMIA) is a 2'-OH selective acylation agent of RNAs, and is widely used forresolving secondary RNA structures using the SHAPE (Selective 2'-Hydroxyl Acylation Analyzed by Primer Extension) technology[1].
[1]. Ursuegui S, et al. Biotin-conjugated N-methylisatoic anhydride: a chemical tool for nucleic acid separation by selective 2'-hydroxyl acylation of RNA. Chem Commun (Camb). 2014 Jun 1;50(43):5748-51.
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