- Cat.No. 상품명 정보
- GC40049 Glucocorticoid Resistance Inhibitor Glucocorticoid resistance inhibitor is an inhibitor of glucocorticoid resistance.
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GP10038
Cyclin dependent kinase inhibitor 2A - Tumor Suppressor
Cyclin dependent kinase inhibitor 2A (CDKN2A, p16Ink4A) (H2N-Met-Val-Arg-Arg-Phe-Leu-Val-Thr-Leu-Arg-Ile-Arg-Arg-Ala-Cys-Gly-Pro-Pro-Arg-Val-OH), also known as multiple tumor suppressor 1 (MTS-1), is a tumor suppressor protein, which in humans is encoded by the CDKN2A gene.
- GC41185 MAGL Inhibitor Compound 23 MAGL 억제제 화합물 23은 80nM의 IC50으로 MAGL의 강력하고 선택적이고 가역적이며 경쟁적인 억제제입니다. MAGL 억제제 화합물 23은 인간 유방암, 결장직장암 및 난소암 세포에 대해 항증식 효과를 나타냅니다. MAGL 억제제 화합물 23은 세포 기반 및 생체 내 분석에서 MAGL을 차단합니다.
- GP10098 Cdk2/Cyclin Inhibitory Peptide I
- GP10022 Dynamin inhibitory peptide
- GC41532 Benzisoxazole Hsp90 Inhibitor Heat shock protein 90 (Hsp90) is a molecular chaperone that modulates intracellular signaling and protein folding, trafficking, and turnover.
- GC40724 Heat Shock Protein Inhibitor II Heat shock protein (Hsp) inhibitor II is the active form of Hsp inhibitor I and a benzylidene lactam compound that prevents the synthesis of inducible Hsps, such as Hsp105, Hsp72, and Hsp40.
- GC48463 Bisubstrate Inhibitor 78 An inhibitor of NNMT
- GC18616 MMP-8 Inhibitor I MMP-8 Inhibitor I is a selective inhibitor of the neutrophil collagenase matrix metalloproteinase-8 (MMP-8) with an IC50 value of 4 nM.
- GC49915 Hexa-D-Arginine (trifluoroacetate salt) A furin inhibitor
- GC49668 SABRAC An inhibitor of acid ceramidase
- GC49664 CB-1158 An arginase inhibitor
- GC49359 IM-156 (acetate) A mitochondrial complex I inhibitor and an AMPKα activator
- GC49347 8Br-HA An FHIT inhibitor
- GC49285 Adenosine 5’-methylenediphosphate (hydrate) An inhibitor of ecto-5’-nucleotidase
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GC49089
FR900359
A cyclic depsipeptide and an inhibitor of Gαq, Gα11, and Gα14
- GC49074 Forphenicine A bacterial metabolite and an inhibitor of alkaline phosphatase
- GC48495 BMS-P5 BMS-P5는 특이적 경구 활성 펩티딜아르기닌 데이미나제 4(PAD4) 억제제입니다. BMS-P5는 동계 마우스 모델에서 MM 유도 NET 형성을 차단하고 MM의 진행을 지연시킵니다.
- GC48406 PSI (trifluoroacetate salt) A proteasome inhibitor
- GC47533 L-778,123 A dual inhibitor of FTase and GGTase I
- GC47064 CAY10770 An inhibitor of CYP4Z1
- GC46184 Nexinhib20 An inhibitor of Rab27a-JFC1 protein-protein interactions
- GC46039 1,2,3,4-Tetrahydrostaurosporine A mutant EGFR inhibitor
- GC45251 (-)-Neplanocin A S-Adenosylhomocysteine (SAH) hydrolase catalyzes the reversible hydrolysis of SAH to adenosine and homocysteine.
- GC45207 α-hydroxy Farnesyl Phosphonic Acid α-hydroxy Farnesyl phosphonic acid is a nonhydrolyzable analog of farnesyl pyrophosphate which acts as a competitive inhibitor of farnesyl transferase (FTase).
- GC45110 UCM53 An inhibitor of bacterial cell division
- GC44975 SW203668 (trifluoroacetate salt) SW203668 is an irreversible inhibitor of stearoyl-CoA desaturase (IC50 = 54 nM).
- GC44637 PHPS1 PHPS1은 Shp2, Shp2-R362K, Shp1, PTP1B 및 PTP1B-Q에 대해 Kis가 각각 0.73, 5.8, 10.7, 5.8 및 0.47 μM인 강력하고 선택적인 Shp2 억제제입니다.
- GC43804 Halofuginone (hydrochloride) Halofuginone is a halogenated derivative of febrifugine, a natural quinazolinone-containing compound found in the Chinese herb D.
- GC43368 D,L-1′-Acetoxychavicol Acetate D,L-1′-Acetoxychavicol acetate is a natural compound first isolated from the rhizomes of ginger-like plants.
- GC43361 Cytostatin (sodium salt) Cytostatin is a natural antitumor inhibitor of cell adhesion to extracellular matrix, blocking adhesion of B16 melanoma cells to laminin and collagen type IV in vitro (IC50s = 1.3 and 1.4 μg/ml, respectively) and B16 cells metastatic activity in mice.
- GC43153 CAY10416 Dual cyclooxygenase-2 (COX-2)/5-lipoxygenase (5-LO) inhibitors are potential therapeutic agents for inflammatory diseases and for prostate cancer.
- GC42644 9-Deazaguanine 9-Deazaguanine is an analog of guanine that acts as an inhibitor of purine nucleoside phosphorylase (PNP; Kd = 160 nM).
- GC42503 5'-deoxy-5-Fluorocytidine 5'-deoxy-5-Fluorocytidine is an intermediate metabolite of the DNA synthesis inhibitor capecitabine.
- GC41518 Sterculic Acid methyl ester Sterculic acid methyl ester is an ester form of sterculic acid, which is an inhibitor of δ9 desaturase.
- GC40890 CAY10701 CAY10701 is a 7-deazahypoxanthine analog that prevents microtubule formation, blocking the proliferation of HeLa and MCF-7 cells (GI50s = 22 and 38 nM, respectively).
- GC40674 APHA Compound 8 A class I and II HDAC inhibitor
- GC18949 CAY10677 Post-translational protein prenylation is a 3-step process that occurs at the C-terminus of a number of proteins involved in cell growth control and oncogenesis.
- GC18789 Lobaric Acid Lobaric acid is a depsidone metabolite that has been isolated from Stereocaulon lichen species with antioxidant, antiproliferative, antiviral, and enzyme inhibitory activites.
- GC18449 Cardanol monoene 카르다놀 모노엔(Cardanol C15:1)은 캐슈넛 껍질 액체에서 찾을 수 있는 페놀 화합물입니다. Cardanol monoene은 인간 흑색종 세포에서 미토콘드리아 관련 세포자멸사를 유도할 수 있습니다.
- GC18271 Polmacoxib 폴마콕시브(CG100649)는 동급 최초의 경구 활성 비스테로이드성 항염증제(NSAID)로 COX-2(IC50 약 0.1μg/ml)와 탄산 탈수효소의 이중 억제제입니다. Polmacoxib는 마우스 모델에서 결장직장 선종 및 종양 성장을 억제합니다.
- GC12948 CID-1067700 CID-1067700(ML282)은 범 GTPase 억제제이며 13 nM의 Ki로 뇌 7(Rab7)에서 Ras 관련 Ras를 경쟁적으로 억제합니다.
- GC13460 2-Hydroxyestradiol 2-Hydroxyestradiol은 에스트로겐 활성이 최소인 17β-estradiol의 대사산물로 항산화 효과가 있으며 DNA와 반응하여 안정한 부가물을 형성하고 유전독성을 나타낸다.
- GC16722 CE3F4 CE3F4는 Epac1 및 Epac2(B)에 대해 각각 10.7μM 및 66μM의 IC50을 갖는 cAMP(Epac1)에 의해 직접 활성화되는 교환 단백질의 선택적 길항제입니다.
- GC11189 AI-10-49 AI-10-49는 CBFβ-SMMHC에 선택적으로 결합하고 0.26μM의 FRET IC50으로 RUNX1에 대한 결합을 방해하는 단백질-단백질 상호작용 억제제이다.
- GC10906 RBC8 RBC8은 Ral GTPase의 새로운 소분자 억제제입니다. IC50은 H2122 셀에서 3.5μM, H358 셀에서 3.4μM입니다.