CYPMPO (Synonyms: RR 071) |
| Catalog No.GC43352 |
CYPMPO는 스핀 트래핑 시약입니다. 고리형 DEPMPO형 니트론인 CYPMPO는 하이드록실 및 슈퍼옥사이드 라디칼에 대한 스핀 트래핑 기능에 대해 평가됩니다. 항산화 및 항종양.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 934182-09-9
Sample solution is provided at 25 µL, 10mM.
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CYPMPO is a free radical spin trap with excellent trapping capabilities toward hydroxyl and superoxide radicals in biological and chemical systems. Decay of the superoxide adduct of CYPMPO proceeds in an apparent first order fashion with half-lives of 15 and 51 minutes in a UV-illuminated hydrogen peroxide solution and a hypoxanthine/xanthine oxidase system, respectively. CYPMPO traps superoxide radicals generated by bovine neutrophils as effectively as DEPMPO.[1] The high melting point (126°C), low hygroscopic properties, and long shelf-life in aqueous solutions offer significant practical advantages for use of CYPMPO over DEPMPO and DMPO.
Reference:
[1]. Kamibayashi, M., Oowada, S., Kameda, H., et al. Synthesis and characterization of a practically better DEPMPO-type spin trap, 5-(2,2-dimethyl-1,3-propoxy cyclophosphoryl)-5-methyl-1-pyrroline N-oxide (CYPMPO). Free Radical Research 40(11), 1166-1172 (2006).
Average Rating: 5 (Based on Reviews and 4 reference(s) in Google Scholar.)
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