DMPAC-Chol (Synonyms: Chol-T) |
| Catalog No.GC40192 |
DMPAC-Chol is a cationic cholesterol derivative that has been used in liposome formation for gene transfection.
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Cas No.: 184582-91-0
Sample solution is provided at 25 µL, 10mM.
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DMPAC-Chol is a cationic cholesterol derivative that has been used in liposome formation for gene transfection. Liposomes containing DMPAC-chol bind to DNA in a band shift assay and protect against serum nuclease degradation of DNA when used at lipsome:DNA ratios ranging from 2.5:1 to 10:1 w/w. DMPAC-Chol-containing liposomes also reduce viability of HepG2 cells by 63% when used at a concentration of 37.5 µg/ml.
Average Rating: 5 (Based on Reviews and 28 reference(s) in Google Scholar.)
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