E3 ligase Ligand-Linker Conjugates 11 (Synonyms: VHL Ligand-Linker Conjugates 11; E3 ligase Ligand-Linker Conjugates 11) |
| Catalog No.GC32986 |
E3 리가제 리간드-링커 접합체 11은 (S,R,S)-AHPC 기반 VHL 리간드 및 2-단위 PEG 링커를 통합하는 소분자 HaloPROTAC입니다. E3 리가제 리간드-링커 접합체 11은 세포 기반 분석에서 GFP-HaloTag7의 분해를 유도할 수 있습니다.
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Cas No.: 1835705-61-7
Sample solution is provided at 25 µL, 10mM.
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E3 Ligase Ligand-Linker Conjugate 11 is a synthesized compound which incorporates a ligand for the E3 ubiquitin ligase and a PROTAC linker to bring together target protein and ubiquitinating machinery.
[1]. Ashton C. Lai, et al. Modular PROTAC Design for the Degradation of Oncogenic BCR-ABL. Angew Chem Int Ed Engl. 2016 Jan 11; 55(2): 807-810.
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