(E)-Ferulic acid |
| Catalog No.GC34980 |
(E)-Ferulic acid는 식물 세포벽에 풍부한 방향족 화합물인 Ferrulic acid의 이성질체입니다. (E)-페룰린산은 β-카테닌의 인산화를 일으켜 β-카테닌의 프로테아좀 분해를 유발하고 pro-apoptotic factor Bax의 발현을 증가시키고 pro-survivin 인자 survivin의 발현을 감소시킨다. (E)-페룰산은 활성산소종(ROS)을 제거하고 지질 과산화를 억제하는 강력한 능력을 보여줍니다. (E)-Ferulic acid는 인간 폐암 세포주 H1299에서 항증식 및 항이동 효과를 모두 발휘합니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 537-98-4
Sample solution is provided at 25 µL, 10mM.
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(E)-Ferulic acid is a isomer of Ferulic acid which is an aromatic compound, abundant in plant cell walls. (E)-Ferulic acid causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic factor Bax and decreases the expression of pro-survival factor survivin. (E)-Ferulic acid shows a potent ability to remove reactive oxygen species (ROS) and inhibits lipid peroxidation. (E)-Ferulic acid exerts both anti-proliferation and anti-migration effects in the human lung cancer cell line H1299[1]. Bax
[1]. Fong Y, et al. Inhibitory effect of trans-ferulic acid on proliferation and migration of human lung cancer cells accompanied with increased endogenous reactive oxygen species and β-catenin instability. Chin Med. 2016 Oct 1;11:45.
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