3'-Demethylnobiletin |
| Catalog No.GC35107 |
Nobiletin의 유도체인 3'-Demethylnobiletin은 감귤류의 폴리메톡시플라보노이드입니다. Nobiletin은 Src, FAK 및 STAT3 신호를 조절하여 항암 활성을 나타내고 종양 혈관 신생을 억제합니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 112448-39-2
Sample solution is provided at 25 µL, 10mM.
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3'-Demethylnobiletin, a derivative of Nobiletin, is a polymethoxyflavonoid in citrus fruits[1]. Nobiletin exhibits anticancer activity and inhibits tumor angiogenesis by regulating Src, FAK, and STAT3 signaling[2].
[1]. Murakami A, et al. In vitro absorption and metabolism of nobiletin, a chemopreventive polymethoxyflavonoid in citrus fruits. Biosci Biotechnol Biochem. 2001 Jan;65(1):194-7. [2]. Sp N, et al. Nobiletin Inhibits Angiogenesis by Regulating Src/FAK/STAT3-Mediated Signaling through PXN in ER+ Breast Cancer Cells. Int J Mol Sci. 2017 Apr 30;18(5). pii: E935.
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