Conteltinib (Synonyms: CT-707) |
| Catalog No.GC35728 |
콘텔티닙(CT-707)은 FAK, ALK 및 Pyk2를 표적으로 하는 다중 키나제 억제제입니다. 콘텔티닙은 1.6nM의 IC50으로 FAK에 상당한 억제 효과를 발휘합니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1384860-29-0
Sample solution is provided at 25 µL, 10mM.
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Conteltinib (CT-707) is a multi-kinase inhibitor targeting FAK, ALK, and Pyk2. Conteltinib (CT-707) exerts significant inhibitory effect on FAK with an IC50 of 1.6 nM[1]. IC50: 1.6 nM (FAK)[1]
[1]. Wang DD, et al. CT-707, a Novel FAK Inhibitor, Synergizes with Cabozantinib to Suppress Hepatocellular Carcinoma by Blocking Cabozantinib-Induced FAK Activation. Mol Cancer Ther. 2016 Dec;15(12):2916-2925.
Average Rating: 5 (Based on Reviews and 23 reference(s) in Google Scholar.)
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