E3 ligase Ligand 11 (Synonyms: E3 ligase Ligand 11) |
Catalog No.GC35925 |
E3 리가제 리간드 11은 LCL161 유도체 기반 IAP 리간드입니다. E3 리가제 리간드 11은 링커에 의해 단백질용 ABL 리간드에 연결되어 SNIPER를 형성할 수 있습니다.
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Cas No.: 2357114-70-4
Sample solution is provided at 25 µL, 10mM.
E3 ligase Ligand 13 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 13 can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].
[1]. Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575.
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