NaV1.7 inhibitor-1 |
| Catalog No.GC36698 |
NaV1.7 억제제-1은 hNaV1.7에 대해 IC50이 0.6nM인 효과적인 전압 개폐 나트륨 채널(NaV) 1.7 억제제이며, hNaV1.5에 대해 80배 선택성을 나타냅니다.
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Cas No.: 1494585-79-3
Sample solution is provided at 25 µL, 10mM.
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NaV1.7 inhibitor-1 is an efficacious voltage-gated sodium channel (NaV) 1.7 inhibitor with an IC50 of 0.6 nM for hNaV1.7, exhibits 80-fold selectivity versus hNaV1.5[1]. IC50: 0.6 nM (hNaV1.7)[1]
[1]. Sun S, Identification of Selective Acyl Sulfonamide-Cycloalkylether Inhibitors of the Voltage-GatedSodium Channel (NaV) 1.7 with Potent Analgesic Activity. J Med Chem. 2019 Jan 24;62(2):908-927.
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