NaV1.7 inhibitor-1 |
| Katalog-Nr.GC36698 |
NaV1.7 Inhibitor-1 ist ein wirksamer spannungsgesteuerter Natriumkanal (NaV) 1.7-Inhibitor mit einem IC50-Wert von 0,6 nM fÜr hNaV1.7 und einer 80-fachen SelektivitÄt gegenÜber hNaV1.5.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1494585-79-3
Sample solution is provided at 25 µL, 10mM.
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NaV1.7 inhibitor-1 is an efficacious voltage-gated sodium channel (NaV) 1.7 inhibitor with an IC50 of 0.6 nM for hNaV1.7, exhibits 80-fold selectivity versus hNaV1.5[1]. IC50: 0.6 nM (hNaV1.7)[1]
[1]. Sun S, Identification of Selective Acyl Sulfonamide-Cycloalkylether Inhibitors of the Voltage-GatedSodium Channel (NaV) 1.7 with Potent Analgesic Activity. J Med Chem. 2019 Jan 24;62(2):908-927.
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