N-p-trans-Coumaroyltyramine |
| Catalog No.GC36770 |
N-p-trans-Coumaroyltyramine은 폴리고눔 히르카니쿰에서 분리된 신나모일페네틸 아미드이며 IC50이 122μM인 아세틸콜린에스테라제(AChE) 억제제로 작용합니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 36417-86-4
Sample solution is provided at 25 µL, 10mM.
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N-p-trans-Coumaroyltyramine is a cinnamoylphenethyl amide isolated from polygonum hyrcanicum, acts as an acetylcholinesterase (AChE) inhibitor with an an IC50 of 122 μM. N-p-trans-Coumaroyltyramine exhibits anti-trypanosomal activity with an IC50 of 13.3 µM for T. brucei rhodesiense[1][2]. IC50: 122 μM (AChE)[2]
[1]. Moradi-Afrapoli F, et al. Cinnamoylphenethyl amides from Polygonum hyrcanicum possess anti-trypanosomal activity. Nat Prod Commun. 2012 Jun;7(6):753-5. [2]. Kim DK, et al. Inhibitory effect of trans-N-p-coumaroyl tryamine from the twigs of Celtis chinensis on the acetylcholinesterase. Arch Pharm Res. 2003 Sep;26(9):735-8.
Average Rating: 5 (Based on Reviews and 29 reference(s) in Google Scholar.)
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