>>Peptides>>Neuromedin N

Neuromedin N (Synonyms: Neuromedin N (rat, mouse, porcine, canine))

Catalog No.GC36726

Neuromedin N은 쥐의 선조체 막에서 도파민 D2 수용체 작용제 결합의 강력한 조절제입니다.

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Neuromedin N Chemical Structure

Cas No.: 92169-45-4

Size 가격 재고 수량
5mg
US$89.00
재고 있음
10mM (in 1mL Water)
US$130.00
재고 있음
25mg
US$278.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Neuromedin N is a potent modulator of dopamine D2 receptor agonist binding in rat neostriatal membranes. Dopamine D2 receptor[1].

Neuromedin N competitively inhibits the binding of neurotensin to rat brain synaptic membranes with a 19-fold lower potency than neurotensin and is rapidly inactivated by brain synaptic peptidases[1]. It competitively inhibits neurotensin binding to rat brain synaptic membranes and has increased potency in the presence of the peptidase inhibitor bestatin[2].

[1]. Li XM, et al. Neuromedin N is a potent modulator of dopamine D2 receptor agonist binding in rat neostriatal membranes. Neurosci Lett. 1993 Jun 11;155(2):121-4. [2]. Checler F, et al. Neuromedin N: high affinity interaction with brain neurotensin receptors and rapid inactivation by brain synaptic peptidases. Eur J Pharmacol. 1986 Jul 31;126(3):239-44.

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