PP7 |
| Catalog No.GC36953 |
PP7은 IC50이 8.6μM인 강력한 PB1-PB2 상호작용 억제제이며 바이러스 폴리머라제 활성에 대한 억제(IC50=9.5μM)입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 433238-84-7
Sample solution is provided at 25 µL, 10mM.
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PP7 is a potent PB1-PB2 interaction inhibitor with an IC50 of 8.6 μM, and their inhibition against viral polymerase activity (IC50=9.5 μM). PP7 shows antiviral activities against influenza A virus (IAV), including A(H1N1)pdm09 (EC50=1.4 μM), A(H7N9) and A(H9N2) subtypes[1]. IC50: 8.6 μM (PB1-PB2 interaction)[1]
[1]. Yuan S, et al. Identification of a novel small-molecule compound targeting the influenza A virus polymerase PB1-PB2 interface. Antiviral Res. 2017 Jan;137:58-66.
Average Rating: 5 (Based on Reviews and 32 reference(s) in Google Scholar.)
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