PP7 |
カタログ番号GC36953 |
PP7 は、8.6 μM の IC50 を持つ強力な PB1-PB2 相互作用阻害剤であり、ウイルスポリメラーゼ活性に対する阻害 (IC50 = 9.5 μM) です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 433238-84-7
Sample solution is provided at 25 µL, 10mM.
PP7 is a potent PB1-PB2 interaction inhibitor with an IC50 of 8.6 μM, and their inhibition against viral polymerase activity (IC50=9.5 μM). PP7 shows antiviral activities against influenza A virus (IAV), including A(H1N1)pdm09 (EC50=1.4 μM), A(H7N9) and A(H9N2) subtypes[1]. IC50: 8.6 μM (PB1-PB2 interaction)[1]
[1]. Yuan S, et al. Identification of a novel small-molecule compound targeting the influenza A virus polymerase PB1-PB2 interface. Antiviral Res. 2017 Jan;137:58-66.
Average Rating: 5
(Based on Reviews and 32 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *