DNA2 inhibitor C5 |
| Catalog No.GC38207 |
DNA2 억제제 C5는 IC50이 20μM인 강력하고 경쟁적이며 특이적인 DNA2 뉴클레아제 활성 억제제입니다. DNA2 억제제 C5는 뉴클레아제, DNA 의존성 ATPase, 헬리카아제 및 DNA2의 DNA 결합 활성을 억제합니다. DNA2 억제제 C5는 복제 스트레스를 유발하는 암 화학 요법에 대한 증감제를 개발하는 유망한 리드 화합물입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 35973-25-2
Sample solution is provided at 25 µL, 10mM.
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DNA2 inhibitor C5 is a potent, competitive and specific inhibitor of DNA2 nuclease activity with an IC50 of 20 μM. DNA2 inhibitor C5 inhibits nuclease, DNA dependent ATPase, helicase, and DNA binding activities of DNA2. DNA2 inhibitor C5 is a promising lead compound to develop sensitizers for cancer chemotherapeutics that cause replication stress[1].
[1]. Binghui Shen, et al. Dna2 inhibitors for cancer treatment. US20170226063A1.
Average Rating: 5 (Based on Reviews and 18 reference(s) in Google Scholar.)
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