P62-mediated mitophagy inducer (Synonyms: PMI) |
| Catalog No.GC38562 |
P62 매개 미토파지 유도제는 파킨을 모집하거나 δψm을 붕괴시키지 않고 미토파지를 활성화하고 완전한 기능의 PINK1/파킨 경로가 없는 세포에서 활성을 유지하는 미토파지 조절제입니다.
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Cas No.: 1809031-84-2
Sample solution is provided at 25 µL, 10mM.
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P62-mediated mitophagy inducer is a mitophagy regulator which activates mitophagy without recruiting Parkin or collapsing δψm and retains activity in cells devoid of a fully functional PINK1/Parkin pathway[1].
[1]. East DA, et al. PMI: a δψm independent pharmacological regulator of mitophagy. Chem Biol. 2014 Nov 20;21(11):1585-96.
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