P62-mediated mitophagy inducer (Synonyms: PMI) |
| Katalog-Nr.GC38562 |
Der P62-vermittelte Mitophagie-Induktor ist ein Mitophagie-Regulator, der die Mitophagie aktiviert, ohne Parkin zu rekrutieren oder δψm zu kollabieren, und die AktivitÄt in Zellen ohne einen voll funktionsfÄhigen PINK1/Parkin-Weg aufrechterhÄlt.
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Cas No.: 1809031-84-2
Sample solution is provided at 25 µL, 10mM.
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P62-mediated mitophagy inducer is a mitophagy regulator which activates mitophagy without recruiting Parkin or collapsing δψm and retains activity in cells devoid of a fully functional PINK1/Parkin pathway[1].
[1]. East DA, et al. PMI: a δψm independent pharmacological regulator of mitophagy. Chem Biol. 2014 Nov 20;21(11):1585-96.
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