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GLP-26

Catalog No.GC38785

GLP-26은 HBV 캡시드 조립 조절제(CAM)이며, Hep AD38 시스템(IC50=3nM)에서 HBV DNA 복제를 억제하고 1μM에서 cccDNA를 >90% 감소시킵니다.

Products are for research use only. Not for human use. We do not sell to patients.

GLP-26 Chemical Structure

Cas No.: 2133017-36-2

Size 가격 재고 수량
10mM (in 1mL DMSO)
US$217.00
재고 있음
1mg
US$89.00
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5mg
US$265.00
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10mg
US$357.00
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25mg
US$552.00
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50mg
US$908.00
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100mg
US$1,465.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

GLP-26 is a HBV capsid assembly modulators (CAM), inhibits HBV DNA replication in Hep AD38 system (IC50=3 nM), and reduces cccDNA by >90% at 1 μM.GLP-26 disrupts the encapsidation of pre-genomic RNA, causes nucleocapsid disassembly and reduces cccDNA pools[1].

GLP-26 (0.7-1.7 μM; 3 days) reduces secreted HBeAg in HepNTCP-DL cells transfected with HBVwild type, with EC50 values of 0.7 μM[2]. Cell Viability Assay[2] Cell Line: HepNTCP-DL cells

[1]. Nijampatnam B, et al. Recent advances in the development of HBV capsid assembly modulators. Curr Opin Chem Biol. 2019 Jun;50:73-79.

리뷰

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Average Rating: 5 ★★★★★ (Based on Reviews and 5 reference(s) in Google Scholar.)

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