HC Toxin (Synonyms: Toxin I (Helminthosporium carbonum)) |
| Catalog No.GC43806 |
고리형 테트라펩티드인 HC 독소는 IC50이 30nM인 강력한 HDAC 억제제입니다. HC Toxin은 종양 세포의 세포 사멸을 유도하고 항암 효과가 있습니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 83209-65-8
Sample solution is provided at 25 µL, 10mM.
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HC Toxin is a cell-permeable, reversible inhibitor of histone deacetylases (HDACs) (IC50 = 30 nM). Through its effects on HDACs, HC toxin has been shown to up-regulate the expression of 15-lipoxygenase-1 in colorectal cancer cells and induce fetal hemoglobin in human primary erythroid cells. HC Toxin is a cyclic tetrapeptide first isolated from H. carbonum (now C. carbonum), a pathogen of maize.
Average Rating: 5 (Based on Reviews and 19 reference(s) in Google Scholar.)
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