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홈 >> Signaling Pathways >> Chromatin/Epigenetics >> Histone Deacetylation

Histone Deacetylation

Products for  Histone Deacetylation

  1. Cat.No. 상품명 정보
  2. GC46628 4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline A building block and synthetic intermediate 4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline Chemical Structure
  3. GC46736 7-Bromoheptanoic Acid A building block 7-Bromoheptanoic Acid Chemical Structure
  4. GC48986 9-hydroxy Stearic Acid A hydroxy fatty acid 9-hydroxy Stearic Acid Chemical Structure
  5. GC48382 Ac-QPKK(Ac)-AMC A fluorogenic substrate for SIRT1, SIRT2, and SIRT3 Ac-QPKK(Ac)-AMC Chemical Structure
  6. GC48775 AES-350 AES-350은 IC50 및 Ki가 각각 0.0244μM 및 0.035μM인 강력한 경구 활성 HDAC6 억제제입니다. AES-350은 또한 각각 0.187μM 및 0.245μM의 IC50 값을 갖는 효소 활성 분석에서 HDAC3, HDAC8에 대한 것입니다. AES-350은 HDAC 억제를 통해 AML 세포에서 세포자멸사를 유발하며 급성 골수성 백혈병(AML) 연구에 사용할 수 있습니다. AES-350 Chemical Structure
  7. GC49393 all-trans-13,14-Dihydroretinol A metabolite of all-trans retinoic acid all-trans-13,14-Dihydroretinol Chemical Structure
  8. GC40674 APHA Compound 8 A class I and II HDAC inhibitor APHA Compound 8 Chemical Structure
  9. GC46892 ATRA-BA Hybrid A prodrug form of all-trans retinoic acid and butyric acid ATRA-BA Hybrid Chemical Structure
  10. GC18408 BML-278 BML-278 is an activator of sirtuin 1 (SIRT1) that has an EC150 value (effective concentration able to increase the enzyme by 150%) of 1 uM. BML-278 Chemical Structure
  11. GC11641 Boc-Lys(Ac)-AMC

    GPCR G2A/GPR132 agonist

     Boc-Lys(Ac)-AMC Chemical Structure
  12. GC48620 BPKDi BPKDi는 PKD1, PKD2 및 PKD3에 대해 각각 1nM, 9nM 및 1nM의 IC50을 갖는 강력한 비피리딜 PKD 억제제입니다. BPKDi Chemical Structure
  13. GC40923 BRD4884 BRD4884는 HDAC1, 2 및 3에 대해 IC50 값이 각각 29nM, 62nM 및 1.09μM인 강력한 HDAC 억제제입니다. BRD4884 Chemical Structure
  14. GC46104 Butyric Acid-d7 An internal standard for the quantification of sodium butyrate Butyric Acid-d7 Chemical Structure
  15. GC43147 CAY10398 CAY10398 is an inhibitor of histone deacetylase (HDAC1) with an IC50 value of 10 μM. CAY10398 Chemical Structure
  16. GC41601 CAY10591 CAY10591은 Sirt1의 강력한 활성제이며 TNF-α를 억제합니다. 용량 의존적 방식으로. CAY10591 Chemical Structure
  17. GC43201 CAY10722 CAY10722 is an inhibitor of sirtuin 3 (SIRT3), a class III HDAC (71% inhibition at 200 μM). CAY10722 Chemical Structure
  18. GC49029 CAY17c An inhibitor of BRD4 and class I and class IIb HDACs CAY17c Chemical Structure
  19. GC43318 coumarin-SAHA Coumarin-SAHA는 HDAC8-억제제 복합체의 결합 친화도(kd) 및 해리 오프율(koff)을 결정하기 위한 형광 프로브입니다. coumarin-SAHA Chemical Structure
  20. GC52368 DL-Sulforaphane Glutathione A metabolite of sulforaphane DL-Sulforaphane Glutathione Chemical Structure
  21. GC43806 HC Toxin 고리형 테트라펩티드인 HC 독소는 IC50이 30nM인 강력한 HDAC 억제제입니다. HC Toxin은 종양 세포의 세포 사멸을 유도하고 항암 효과가 있습니다. HC Toxin Chemical Structure
  22. GC41495 HDAC3 Inhibitor HDAC3 억제제(화합물 5)는 IC50이 5.96nM인 강력하고 선택적인 HDAC3 억제제입니다. HDAC3 Inhibitor Chemical Structure
  23. GC49693 HDAC5 (human, recombinant) Active, pure human recombinant enzyme HDAC5 (human, recombinant) Chemical Structure
  24. GC47579 L-Pyrohomoglutamic Acid An amino acid building block L-Pyrohomoglutamic Acid Chemical Structure
  25. GC52188 MDL 800 MDL 800 Chemical Structure
  26. GC48805 Methapyrilene (hydrochloride) 메타피릴렌(Thenylpyramine) 염산염은 경구 활성 H1 수용체 항히스타민제이며 피리딘 화학 계열의 항콜린제입니다. Methapyrilene (hydrochloride) Chemical Structure
  27. GC49270 Nicotinamide-d4 Nicotinamide-d4 (Niacinamide-d4)는 Nicotinamide로 표시된 중수소입니다. Nicotinamide-d4 Chemical Structure
  28. GC52166 NN-390 NN-390은 IC50이 9.8nM인 강력하고 선택적인 HDAC6 억제제입니다. NN-390은 혈액뇌장벽(BBB)을 관통합니다. NN-390은 전이성 그룹 3 MB(수모세포종)에서 연구 가능성을 보여줍니다. NN-390 Chemical Structure
  29. GC48460 NR-160 An inhibitor of HDAC6 NR-160 Chemical Structure
  30. GC49815 Oleuropein aglycone A polyphenol with diverse biological activities Oleuropein aglycone Chemical Structure
  31. GC44865 SAHA-BPyne Suberoylanilide hydroxamic acid (SAHA) is a class I and class II histone deacetylase (HDAC) inhibitor that binds directly to the catalytic site of the enzyme thereby blocking substrate access. SAHA-BPyne Chemical Structure
  32. GC44866 SAHA-d5 SAHA-d5(SAHA-d5)는 Vorinostat로 표시된 중수소입니다. SAHA-d5 Chemical Structure
  33. GC48084 Sodium 4-Phenylbutyrate-d11 Phenylbutyrate-d11(나트륨)은 중수소로 표지된 Sodium 4-phenylbutyrate입니다. 4-페닐부티르산 나트륨(4-PBA 나트륨)은 암 및 감염 연구에 사용되는 HDAC 및 소포체(ER) 스트레스의 억제제입니다. Sodium 4-Phenylbutyrate-d11 Chemical Structure
  34. GC46226 SS-208 SS-208은 IC50이 12nM인 선택적 HDAC6 억제제입니다. SS-208은 흑색종에서 항종양 활성을 가지고 있습니다. SS-208 Chemical Structure
  35. GC18915 Trapoxin A Trapoxin A is a cyclotetrapeptide histone deacetylase (HDAC) inhibitor. Trapoxin A Chemical Structure
  36. GC45080 Trichostatin C Trichostatin C is a glycosylated derivative of trichostatin A, the antifungal antibiotic that reversibly inhibits histone deacetylase. Trichostatin C Chemical Structure
  37. GC45095 Tubastatin A (trifluoroacetate salt) Tubastatin A is a potent HDAC6 inhibitor with an IC50 value of 15 nM. Tubastatin A (trifluoroacetate salt) Chemical Structure
  38. GC48408 TW9 A dual inhibitor of BRD4 and HDAC1 TW9 Chemical Structure
  39. GC45137 Valproic Acid Acyl-D-Glucuronide Valproic acid acyl-D-glucuronide is the major urinary metabolite of valproic acid. Valproic Acid Acyl-D-Glucuronide Chemical Structure

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