Hydroxygenkwanin (Synonyms: HGK, Luteolin 7-methyl ether, 7-O-Methylluteolin) |
Catalog No.GC38795 |
천연 플라보노이드 화합물인 Hydroxygenkwanin(7-O-Methylluteolin)은 라일락 다프네의 주성분 중 하나입니다. Hydroxygenkwanin은 항산화 능력, 항신경교종 능력 및 항암 효과가 있습니다.
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Cas No.: 20243-59-8
Sample solution is provided at 25 µL, 10mM.
Hydroxygenkwanin (7-O-Methylluteolin), a natural flavonoid compound, is one of the main components of Lilac Daphne. Hydroxygenkwanin has anti-oxidant ability, anti-glioma ability and anticancer effect[1][2].
Hydroxygenkwanin (7-O-Methylluteolin) inhibits C6 glioma cell proliferation in a dose dependent manner[1]. Hydroxygenkwanin induces the cell cycle arrest by flow cytometry and inhibits colony formation ability and cell movement. Hydroxygenkwanin induces cell cycle arrest through p21 activation and causes intrinsic cell apoptosis pathway[2].
[1]. Wang Y, et al. Synergistic anti-glioma effect of Hydroxygenkwanin and Apigenin in vitro. Chem Biol Interact. 2013 Nov 25;206(2):346-55. [2]. Huang YC, et al. Anticancer Effect and Mechanism of Hydroxygenkwanin in Oral Squamous Cell Carcinoma. Front Oncol. 2019 Sep 18;9:911.
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