Hydroxygenkwanin (Synonyms: HGK, Luteolin 7-methyl ether, 7-O-Methylluteolin) |
| カタログ番号GC38795 |
天然のフラボノイド化合物であるヒドロキシゲンクワニン (7-O-メチルルテオリン) は、ライラック ダフネの主要成分の 1 つです。ヒドロキシゲンクワニンには、抗酸化能、抗グリオーマ能、抗がん作用があります。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 20243-59-8
Sample solution is provided at 25 µL, 10mM.
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Hydroxygenkwanin (7-O-Methylluteolin), a natural flavonoid compound, is one of the main components of Lilac Daphne. Hydroxygenkwanin has anti-oxidant ability, anti-glioma ability and anticancer effect[1][2].
Hydroxygenkwanin (7-O-Methylluteolin) inhibits C6 glioma cell proliferation in a dose dependent manner[1]. Hydroxygenkwanin induces the cell cycle arrest by flow cytometry and inhibits colony formation ability and cell movement. Hydroxygenkwanin induces cell cycle arrest through p21 activation and causes intrinsic cell apoptosis pathway[2].
[1]. Wang Y, et al. Synergistic anti-glioma effect of Hydroxygenkwanin and Apigenin in vitro. Chem Biol Interact. 2013 Nov 25;206(2):346-55. [2]. Huang YC, et al. Anticancer Effect and Mechanism of Hydroxygenkwanin in Oral Squamous Cell Carcinoma. Front Oncol. 2019 Sep 18;9:911.
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