Methyl cinnamate |
Catalog No.GC38815
One-Click Copy Product Info
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Zanthoxylum armatum의 활성 성분인 메틸 신나메이트(Methyl 3-phenylpropenoate)는 널리 사용되는 천연 향료 화합물입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 103-26-4
Sample solution is provided at 25 µL, 10mM.
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Methyl cinnamate (Methyl 3-phenylpropenoate), an active component of Zanthoxylum armatum, is a widely used natural flavor compound. Methyl cinnamate (Methyl 3-phenylpropenoate) possesses antimicrobial activity and is a tyrosinase inhibitor that can prevent food browning. Methyl cinnamate (Methyl 3-phenylpropenoate) has antiadipogenic activity through mechanisms mediated, in part, by the CaMKK2-AMPK signaling pathway[1].
In 3T3-L1 cell model, Methyl cinnamate (Methyl 3-phenylpropenoate) inhibits adipocyte differentiation by attenuating expression of the adipogenic transcription factors SREBP-1, PPARγ, and C/EBPα and the transcriptional activity of PPARγ. In addition, Methyl cinnamate (Methyl 3-phenylpropenoate) activates the CaMKK2-AMPK signaling cascade involved in the regulation of adipogenesis[1].
[1]. Chen YY, et al. Methyl cinnamate inhibits adipocyte differentiation via activation of the CaMKK2-AMPK pathwayin 3T3-L1 preadipocytes. J Agric Food Chem. 2012 Feb 1;60(4):955-63.
| Cas No. | 103-26-4 | SDF | |
| Canonical SMILES | O=C(OC)/C=C/C1=CC=CC=C1 | ||
| Formula | C10H10O2 | M.Wt | 162.19 |
| Solubility | DMSO: ≥ 100 mg/mL (616.56 mM); Water: 1 mg/mL (6.17 mM) | Storage | Store at -20°C |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 6.1656 mL | 30.828 mL | 61.6561 mL |
| 5 mM | 1.2331 mL | 6.1656 mL | 12.3312 mL |
| 10 mM | 616.6 μL | 3.0828 mL | 6.1656 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >99.00% Appearance: A Liquid
- COA (Certificate of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 15 reference(s) in Google Scholar.)