>>Signaling Pathways>> Metabolism>>ML-309 (hydrochloride)

ML-309 (hydrochloride)

Catalog No.GC44224

ML-309 is an inhibitor of mutant isocitrate dehydrogenase 1 (IDH1).

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ML-309 (hydrochloride) Chemical Structure

Cas No.: 1355327-02-4

Size 가격 재고 수량
1mg
US$54.00
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5mg
US$146.00
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10mg
US$265.00
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

ML-309 is an inhibitor of mutant isocitrate dehydrogenase 1 (IDH1). It reversibly and selective inhibits IDH1R132H over wild-type IDH1 (IC50s = 96 and 36,500 nM, respectively). ML-309 reduces 2-hydroxyglutarate production in U87 MG glioblastoma cells (EC50 = 55 nM).

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Average Rating: 5 ★★★★★ (Based on Reviews and 31 reference(s) in Google Scholar.)

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