ML-309 (hydrochloride) |
カタログ番号GC44224 |
ML-309は、変異型イソシトレートデヒドロゲナーゼ1(IDH1)の阻害剤です。
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Cas No.: 1355327-02-4
Sample solution is provided at 25 µL, 10mM.
ML-309 is an inhibitor of mutant isocitrate dehydrogenase 1 (IDH1). It reversibly and selective inhibits IDH1R132H over wild-type IDH1 (IC50s = 96 and 36,500 nM, respectively). ML-309 reduces 2-hydroxyglutarate production in U87 MG glioblastoma cells (EC50 = 55 nM).
Review for ML-309 (hydrochloride)
Average Rating: 5
(Based on Reviews and 31 reference(s) in Google Scholar.)Review for ML-309 (hydrochloride)
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