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ML-309 (hydrochloride)

カタログ番号GC44224

ML-309は、変異型イソシトレートデヒドロゲナーゼ1(IDH1)の阻害剤です。

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ML-309 (hydrochloride) 化学構造

Cas No.: 1355327-02-4

サイズ 価格 在庫数 個数
1mg
$54.00
在庫あり
5mg
$146.00
在庫あり
10mg
$265.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

ML-309 is an inhibitor of mutant isocitrate dehydrogenase 1 (IDH1). It reversibly and selective inhibits IDH1R132H over wild-type IDH1 (IC50s = 96 and 36,500 nM, respectively). ML-309 reduces 2-hydroxyglutarate production in U87 MG glioblastoma cells (EC50 = 55 nM).

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Average Rating: 5 ★★★★★ (Based on Reviews and 31 reference(s) in Google Scholar.)

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