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ML-309 (hydrochloride)

Katalog-Nr.GC44224

ML-309 is an inhibitor of mutant isocitrate dehydrogenase 1 (IDH1).

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ML-309 (hydrochloride) Chemische Struktur

Cas No.: 1355327-02-4

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5mg
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

ML-309 is an inhibitor of mutant isocitrate dehydrogenase 1 (IDH1). It reversibly and selective inhibits IDH1R132H over wild-type IDH1 (IC50s = 96 and 36,500 nM, respectively). ML-309 reduces 2-hydroxyglutarate production in U87 MG glioblastoma cells (EC50 = 55 nM).

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