Py-BODIPY-NHS ester |
| Catalog No.GC60313 |
Py-BODIPY-NHS 에스테르는 세포 투과성 및 형광성 에너지 전달 프로브입니다. Py-BODIPY-NHS 에스테르 추적자는 강력한 세포 결합을 생성하고 MET 키나제에 최적인 것으로 입증되었습니다. 살아있는 세포 에너지 전달 기술은 세포 내 키나아제 표적 결합에 대한 광범위한 범위의 정량 분석을 수행할 수 있습니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 201998-61-0
Sample solution is provided at 25 µL, 10mM.
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Py-BODIPY-NHS ester is a cell-permeable and fluorescent energy transfer probe. Py-BODIPY-NHS ester tracer yields strong cellular engagement and proves to be optimal for MET kinase. The live-cell energy transfer technique can perform a broad-coverage, quantitative analysis of intracellular kinase target engagement[1][2].
Triphenylphosphonium-fluorochromes (TPP-fluorochromes) are a new class of spectrally variable, mitochondrially targeted probes. NanoBRET 590 SE (compound 2b) is synthesized by reacting the TPP-amine with NHS esters of BODIPY red[3].
[1]. Vasta JD, et al. Quantitative, Wide-Spectrum Kinase Profiling in Live Cells for Assessing the Effect of CellularATP on Target Engagement. Cell Chem Biol. 2018 Feb 15;25(2):206-214.e11. [2]. Robers MB, et al. Quantitative, Real-Time Measurements of Intracellular Target Engagement Using Energy Transfer. Methods Mol Biol. 2019;1888:45-71. [3]. Yuan H, et al. Fluorescent and radiolabeled triphenylphosphonium probes for imaging mitochondria. Chem Commun (Camb). 2013 Nov 14;49(88):10361-3.
Average Rating: 5 (Based on Reviews and 23 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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