Remdesivir (GS-5734) (Synonyms: GS-5734) |
| Catalog No.GC32223 |
렘데시비르 (GS-5734)는 효과적인 항바이러스 활성을 가진 뉴클레오사이드 아날로그로, SARS-CoV-2 및 그 변종 알파, 베타, 감마 및 델타에 대한 EC50은 각각 3.3 μM, 4.7 μM, 32 μM, 3.7 μM 및 9.2 μM입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1809249-37-3
Sample solution is provided at 25 µL, 10mM.
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Remdesivir is a nucleoside analogue, with effective antiviral activity, with EC50s of 74 nM for ARS-CoV and MERS-CoV in HAE cells, and 30 nM for murine hepatitis virus in delayed brain tumor cells.
Remdesivir (GS-5734) is a potent antiviral agent. Remdesivir inhibits murine hepatitis virus (MHV) with an EC50 of 30 nM, and blocks SARS-CoV and MERS-CoV in HAE cells with EC50s of both 74 nM in HAE cells after treatment for 24 h[1].
References
[1]. Agostini ML, et al. Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease. MBio. 2018 Mar 6;9(2). pii: e00221-18.
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