Remdesivir (GS-5734) (Synonyms: GS-5734) |
| カタログ番号GC32223 |
レムデシビル（GS-5734）は、効果的な抗ウイルス活性を持つヌクレオシドアナログであり、SARS-CoV-2およびその変異体α、β、γおよびδに対するEC50はそれぞれ3.3μM、4.7μM、32μM、3.7μMおよび9.2μMです。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1809249-37-3
Sample solution is provided at 25 µL, 10mM.
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Remdesivir is a nucleoside analogue, with effective antiviral activity, with EC50s of 74 nM for ARS-CoV and MERS-CoV in HAE cells, and 30 nM for murine hepatitis virus in delayed brain tumor cells.
Remdesivir (GS-5734) is a potent antiviral agent. Remdesivir inhibits murine hepatitis virus (MHV) with an EC50 of 30 nM, and blocks SARS-CoV and MERS-CoV in HAE cells with EC50s of both 74 nM in HAE cells after treatment for 24 h[1].
References
[1]. Agostini ML, et al. Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease. MBio. 2018 Mar 6;9(2). pii: e00221-18.
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