Cardiovascular
Cardiovascular
The cardiovascular system consists of the heart, blood and blood vessels. These organs form the 3 major closed circulation systems in the body, i.e., the pulmonary, coronary and systemic circulations. Cardiovascular disease includes heart disease, vascular diseases of the brain and kidney, and peripheral arterial diseases. Cardiovascular disease is the leading cause of death globally. Studies on cardiovascular regulation are important to provide a better understanding of this group of diseases and to help improve the corresponding treatment.
Targets for Cardiovascular
Products for Cardiovascular
- Cat.No. 상품명 정보
- GC48612 Propafenone-d5 (hydrochloride) An internal standard for the quantification of propafenone
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GC47980
Propionyl-L-carnitine-d3 (chloride)
An internal standard for the quantification of propionyl-L-carnitine
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GC18310
Prostaglandin A1
Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen.
- GC18855 Prostaglandin A1 ethyl ester Prostaglandin A1 (PGA1) ethyl ester is a prodrug form of PGA1 with enhanced lipid solubility.
- GC40340 Prostaglandin A1 methyl ester Prostaglandin A1 (PGA1) has been shown to cause renal vasodilation, increase urine sodium excretion, and lowers arterial pressure in hypertensive patients.
- GC18353 Prostaglandin A2 A naturally occurring prostaglandin with antiviral/antitumor activity
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GC18411
Prostaglandin B2
Prostaglandin B2 (PGB2) is a non-enzymatic dehydration product resulting from the treatment of PGE2 or PGA2 with strong base.
- GC18999 Prostaglandin D1 Prostaglandin D1 (PGD1) is the theoretical D-series metabolite of DGLA, but to date it has not been isolated as a natural product.
- GC41170 Prostaglandin D2 methyl ester Prostaglandin D2 (PGD2) is the major eicosanoid product of mast cells and is produced in large quantities by hematopoietic PGD synthase during allergic and asthmatic anaphylaxis.
- GC40610 Prostaglandin D3 Prostaglandin D3 (PGD3) is produced by the metabolism of EPA via the COX pathway.
- GC18768 Prostaglandin E1 ethyl ester Prostaglandin E1 (PGE1) is the theoretical cyclooxygenase metabolite of dihomo-γ-linolenic acid.
- GC44728 Prostaglandin I3 (sodium salt) PGI3 is synthesized from EPA by COX and PGI synthase.
- GC49873 Protectin D1 methyl ester An esterified form of protectin D1
- GP10053 Prothrombin (474-477) [Mus musculus]
- GC44732 Protopine (hydrochloride) Protopine is an alkaloid found in Berberidaceae, Ranunculaceae, Rutaceae, Fumariaceae, and Papaveraceae with diverse biological activities.
- GC48406 PSI (trifluoroacetate salt) A proteasome inhibitor
- GC48356 Psychotridine An alkaloid with diverse biological activities
- GC49424 Pyridostigmine-d3 (bromide) An internal standard for the quantification of pyridostigmine
- GC45903 Quazinone A PDE3 inhibitor
- GC48513 Quinapril-d5 An internal standard for the quantification of quinapril
- GC52034 Quinaprilat 퀴나프릴라트는 퀴나프릴의 활성 대사산물인 경구 활성 비메르캅토 안지오텐신 전환 효소(ACE) 억제제입니다.
- GC44799 Quinidine N-oxide Quinidine N-oxide is a pharmacologically inactive quinidine metabolite.
- GC45817 Quinidine-d3 An internal standard for the quantification of quinidine
- GC44801 R-(-)-Flecainide R-(-)-Flecainide is the (R) enantiomer of the antiarrhythmic agent flecainide.
- GC44803 rac-7-hydroxy Propranolol (hydrochloride) rac-7-hydroxy Propranolol (hydrochloride) is a ring-hydroxylated isomer and metabolite of propranolol that is an antagonist at β-adrenergic receptors (0.95 potency relative to propranolol).
- GC40967 rac-7-methoxy Propranolol Propranolol, one of the first β-blockers used in cardiovascular medicine, inhibits β1-, β2-, and β3-adrenergic receptors with log KD values of -8.16, -9.08, and -6.93, respectively.
- GC49291 rac-N-desmethyl Ivabradine-d6 (hydrochloride) An internal standard for the quantification of N-desmethyl ivabradine
- GC49108 Racecadotril-d5 An internal standard for the quantification of racecadotril
- GC49653 Ramipril Diketopiperazine A potential impurity found in commercial preparations of ramipril
- GC49408 Ramipril Diketopiperazine Acid A potential impurity found in commercial preparations of ramipril
- GC40234 Ramipril-d5 Ramipril-d5 is intended for use as an internal standard for the quantification of ramipril by GC- or LC-MS.
- GC40235 Ranolazine-d5 Ranolazine-d5 is intended for use as an internal standard for the quantification of ranolazine by GC- or LC-MS.
- GC48972 Resolvin E2 A specialized pro-resolving mediator
- GC48052 Rilmenidine-d4 An internal standard for the quantification of rilmenidine
- GC60326 Rivaroxaban D4 Rivaroxaban D4(BAY 59-7939 D4)는 Rivaroxaban이라고 표시된 중수소입니다.
- GC49413 Rizatriptan N-oxide A potential impurity found in commercial preparations of rizatriptan
- GC48583 Rizatriptan-d6 (benzoate salt) An internal standard for the quantification of rizatriptan
- GC49107 Rosuvastatin lactone The lactone form of rosuvastatin
- GC48060 Rosuvastatin-d6 (sodium salt) An internal standard for the quantification of rosuvastatin
- GC49190 Roxadustat-d5 록사두스타트-d5는 록사두스타트 라벨이 붙은 중수소입니다. 록사두스타트는 내인성 적혈구생성인자 증가, 철 조절 개선, 헵시딘 감소를 통해 적혈구 생성을 촉진하는 경구 저산소증 유발 인자 프롤릴-하이드록실라제 억제제(HIF-PHI)입니다.
- GC44860 S1QEL1.1 S1QEL1.1 is a small molecule that suppresses superoxide production during reverse electron transport through the IQ site of the mitochondrial respiratory complex I (IC50 = 70 nM) without affecting oxidative phosphorylation.
- GC49093 Safflower Red A red pigment with diverse biological activities
- GC44868 Salbutamol (hydrochloride) Levalbuterol ((R)-Albuterol) 염산염은 Salbutamol의 속효성 β2-아드레날린 수용체 작용제이자 활성 (R)-거울상 이성질체입니다.
- GC45558 Salbutamol-d9
- GC49679 Sauvagine (trifluoroacetate salt) A neuropeptide hormone
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GC49333
SH-42
DHCR24의 억제제
- GC49358 Sildenafil Chlorosulfonyl An intermediate in the synthesis of sildenafil
- GC48078 Sildenafil-d3 실데나필-d3은 실데나필-d3으로 표지된 중수소입니다.
- GC50196 Simvastatin - d6 Deuterated simvastatin
- GC49002 Sinigrin (hydrate) 시니그린(수화물)은 십자화과과 식물에 존재하는 천연 지방족 글루코시놀레이트입니다.
- GC44910 Sodium Hydrogen Sulfide (hydrate) Hydrogen sulfide (H2S) is, like nitric oxide, an important gaseous mediator that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals.
- GC49341 Spermidine-d6 An internal standard for the quantification of spermidine
- GC52390 Spexin 1 (human, mouse, rat, bovine) (acetate) An endogenous peptide and agonist of GAL2 and GAL3
- GC52233 SSPalmO-Phe An ionizable cationic self-degradable SSPalm
- GC52011 Stearic Acid glycidyl ester An esterified form of stearic acid
- GC49770 Stearic Acid glycidyl ester-d5 An internal standard for the quantification of stearic acid glycidyl ester
- GC52112 Stercobilinogen (technical grade) A metabolite of bilirubin and a precursor in the biosynthesis of stercobilin
- GC49500 Stobadine A pyridoindole antioxidant
- GC48117 Sumatriptan-d6 (succinate) An internal standard for the quantification of sumatriptan
- GC52125 T-1095 T-1095는 인간 SGLT1 및 SGLT2에 대해 IC50이 각각 22.8μM 및 2.3μM인 선택적 및 경구 활성 Na+-glucose cotransporter(SGLT) 억제제입니다.
- GC48121 Tadalafil-d3 An internal standard for the quantification of tadalafil
- GC52460 tcY-NH2 (trifluoroacetate salt) A peptide antagonist of PAR4
- GC45007 Telmisartan Acyl-β-D-Glucuronide Telmisartan acyl-β-D-glucuronide is a major metabolite of the angiotensin II receptor antagonist telmisartan.
- GC52478 Telmisartan Acyl-β-D-Glucuronide (hydrate) A major metabolite of telmisartan
- GC48137 Telmisartan-d3 An internal standard for the quantification of telmisartan
- GC18202 Temocaprilat An ACE inhibitor
- GC49386 Tepoxalin 테폭살린은 COX와 5-LO(5-lipoxygenase)의 이중 억제제로서 강력한 항염증 활성과 유리한 위장 프로필을 가지고 있습니다.
- GC45017 Terpendole C Albophoma yamanashiensis가 생산하는 Terpendole C는 아실-CoA: 콜레스테롤 아실트랜스퍼라제(ACAT)에 대한 강력한 억제 활성을 나타냅니다.
- GC48162 Theobromine-d6 An internal standard for the quantification of theobromine
- GC48174 Thiorphan-d5 An internal standard for the quantification of thiorphan
- GP10085 Thrombin Receptor Activator for Peptide 5 (TRAP-5)
- GC45050 Thrombin Receptor Agonist Peptide (trifluoroacetate salt) Thrombin receptor agonist peptide (TRAP-14) is a 14-amino acid peptide agonist of the α-thrombin receptor.
- GC45051 Thrombin Receptor Peptide Ligand (trifluoroacetate salt) Thrombin receptor peptide ligand is antagonist of the thrombin receptor (EC50s = 16-33 μM to inhibit platelet aggregation in vitro).
- GC52254 Thrombin-Sensitive Peptide (ammonium acetate salt) A synthetic peptide containing a thrombin-releasable quencher
- GC48180 Ticagrelor-d7 An internal standard for the quantification of ticagrelor
- GC49076 Tilmicosin-d3 An internal standard for the quantification of tilmicosin
- GC49062 Tiopronin-d3 티오프로닌-d3은 티오프로닌으로 표시된 중수소입니다.
- GC45057 TIQ-A TIQ-A는 TNKS2에 대해 IC50이 24nM인 강력한 TNKS(폴리-ART, PARP) 억제제입니다.
- GC19438 TMB 8 (hydrochloride) TMB 8 is a non-competitive antagonist of nicotinic acetylcholine receptors (nAChRs) with IC50 values of 390 and 350 nM, respectively, for human muscle-type and α3β4 subunit-containing ganglionic nAChRs expressed in TE671/RD or SH-SY5Y cells.
- GC45060 TMP-153 Acyl-CoA:cholesterol acyltransferase (ACAT) catalyses the esterification of excess cellular cholesterol with fatty acids and is important for intestinal cholesterol absorption, hepatic lipoprotein secretion, and cholesterol accumulation in vascular tissues.
- GC48186 Tolvaptan-d7 톨밥탄-D7(OPC-41061-D7)은 톨밥탄으로 표시된 중수소입니다.
- GC48187 Torasemide-d7 An internal standard for the quantification of torasemide
- GC46233 Trandolaprilat (hydrate) 트란돌라프릴라트(수화물)는 강력한 안지오텐신 전환 효소(ACE) 억제제입니다.
- GC52436 TRAP-6 amide (trifluoroacetate salt) A peptide PAR1 agonist
- GC45073 TRAP-6 Peptide (trifluoroacetate salt) TRAP-6 peptide is a hexapeptide corresponding to residues 42-47 of protease-activated receptor 1 (PAR1).
- GC48202 Treprostinil (diethanolamine salt) 트레프로스티닐(UT-15C) 디에탄올아민은 EP2, DP1, IP, EP1, FP4, EP3에 대해 각각 3.6, 4.4, 32.1, 212, 826, 2505 및 4680nM의 Ki 값을 갖는 강력한 EP2, DP1 및 IP 작용제입니다. .
- GC49141 Triacontanoic Acid A very long-chain saturated fatty acid
- GC52005 Triazolomethylindole-3-acetic Acid A metabolite of rizatriptan
- GC49072 Tribenoside Tribenoside는 혈관 보호제이며 치질 연구에 사용할 수 있습니다.
- GC49884 Trigonelline-d3 (chloride) An internal standard for the quantification of trigonelline
- GC48206 Trimethylamine-d9 N-oxide An internal standard for the quantification of trimethylamine N-oxide
- GC45090 Triparanol Triparanol is a 24-dehydro cholesterol reductase (DHCR24) inhibitor (Ki = 0.523 μM), which is an enzyme involved in the biosynthesis of cholesterol.
- GC49389 Tritylolmesartan Medoxomil An intermediate in the synthesis of olmesartan medoxomil
- GC45096 Tyr-α-CGRP (human) (trifluoroacetate salt) Tyr-α-CGRP is an N-terminal extended tyrosinated analogue of α-calcitonin gene-related peptide.
- GC18962 U-92016A U-92016A는 강력하고 대사적으로 안정하며 경구 활성이 있는 5-HT1A 수용체 작용제로서 매우 높은 수준의 고유 활성을 가지고 있습니다.
- GC49328 UDP-α-D-Galactose (sodium salt) A nucleotide sugar
- GC45126 Uric Acid (sodium salt) 산소 라디칼의 제거제인 요산(나트륨염)(요산나트륨)은 혈압의 안정성과 항산화 스트레스를 유지하는 데 도움이 되는 매우 중요한 항산화제입니다.
- GC49812 Urobilin (hydrochloride) A byproduct of hemoglobin degradation
- GC18231 Urocortin II (human) (trifluoroacetate salt) Urocortin II is a neuropeptide hormone and member of the corticotropin-releasing factor (CRF) family which includes mammalian CRF , urocortin , urocortin III , frog sauvagine, and piscine urotensin I.
- GC45130 Urodilatin Urodilatin is a renal natriuretic peptide first isolated from human urine.