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Home >> Signaling Pathways >> Cardiovascular

Cardiovascular

Cardiovascular

Cardiovascular

The cardiovascular system consists of the heart, blood and blood vessels. These organs form the 3 major closed circulation systems in the body, i.e., the pulmonary, coronary and systemic circulations. Cardiovascular disease includes heart disease, vascular diseases of the brain and kidney, and peripheral arterial diseases. Cardiovascular disease is the leading cause of death globally. Studies on cardiovascular regulation are important to provide a better understanding of this group of diseases and to help improve the corresponding treatment.

Targets for  Cardiovascular

Products for  Cardiovascular

  1. Cat.No. Product Name Information
  2. GC48612 Propafenone-d5 (hydrochloride) An internal standard for the quantification of propafenone Propafenone-d5 (hydrochloride) Chemical Structure
  3. GC47980 Propionyl-L-carnitine-d3 (chloride)

    An internal standard for the quantification of propionyl-L-carnitine

     Propionyl-L-carnitine-d3 (chloride) Chemical Structure
  4. GC18310 Prostaglandin A1

    Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen.

     Prostaglandin A1 Chemical Structure
  5. GC18855 Prostaglandin A1 ethyl ester Prostaglandin A1 (PGA1) ethyl ester is a prodrug form of PGA1 with enhanced lipid solubility. Prostaglandin A1 ethyl ester Chemical Structure
  6. GC40340 Prostaglandin A1 methyl ester Prostaglandin A1 (PGA1) has been shown to cause renal vasodilation, increase urine sodium excretion, and lowers arterial pressure in hypertensive patients. Prostaglandin A1 methyl ester Chemical Structure
  7. GC18353 Prostaglandin A2 A naturally occurring prostaglandin with antiviral/antitumor activity Prostaglandin A2 Chemical Structure
  8. GC18411 Prostaglandin B2

    Prostaglandin B2 (PGB2) is a non-enzymatic dehydration product resulting from the treatment of PGE2 or PGA2 with strong base.

     Prostaglandin B2 Chemical Structure
  9. GC18999 Prostaglandin D1 Prostaglandin D1 (PGD1) is the theoretical D-series metabolite of DGLA, but to date it has not been isolated as a natural product. Prostaglandin D1 Chemical Structure
  10. GC41170 Prostaglandin D2 methyl ester Prostaglandin D2 (PGD2) is the major eicosanoid product of mast cells and is produced in large quantities by hematopoietic PGD synthase during allergic and asthmatic anaphylaxis. Prostaglandin D2 methyl ester Chemical Structure
  11. GC40610 Prostaglandin D3 Prostaglandin D3 (PGD3) is produced by the metabolism of EPA via the COX pathway. Prostaglandin D3 Chemical Structure
  12. GC18768 Prostaglandin E1 ethyl ester Prostaglandin E1 (PGE1) is the theoretical cyclooxygenase metabolite of dihomo-γ-linolenic acid. Prostaglandin E1 ethyl ester Chemical Structure
  13. GC44728 Prostaglandin I3 (sodium salt) PGI3 is synthesized from EPA by COX and PGI synthase. Prostaglandin I3 (sodium salt) Chemical Structure
  14. GC49873 Protectin D1 methyl ester An esterified form of protectin D1 Protectin D1 methyl ester Chemical Structure
  15. GP10053 Prothrombin (474-477) [Mus musculus] Prothrombin (474-477) [Mus musculus] Chemical Structure
  16. GC44732 Protopine (hydrochloride) Protopine is an alkaloid found in Berberidaceae, Ranunculaceae, Rutaceae, Fumariaceae, and Papaveraceae with diverse biological activities. Protopine (hydrochloride) Chemical Structure
  17. GC48406 PSI (trifluoroacetate salt) A proteasome inhibitor PSI (trifluoroacetate salt) Chemical Structure
  18. GC48356 Psychotridine An alkaloid with diverse biological activities Psychotridine Chemical Structure
  19. GC49424 Pyridostigmine-d3 (bromide) An internal standard for the quantification of pyridostigmine Pyridostigmine-d3 (bromide) Chemical Structure
  20. GC45903 Quazinone A PDE3 inhibitor Quazinone Chemical Structure
  21. GC48513 Quinapril-d5 An internal standard for the quantification of quinapril Quinapril-d5 Chemical Structure
  22. GC52034 Quinaprilat Quinaprilat is an orally active non-mercapto Angiotensin Converting Enzyme (ACE) inhibitor, the active metabolite of Quinapril. Quinaprilat Chemical Structure
  23. GC44799 Quinidine N-oxide Quinidine N-oxide is a pharmacologically inactive quinidine metabolite. Quinidine N-oxide Chemical Structure
  24. GC45817 Quinidine-d3 An internal standard for the quantification of quinidine Quinidine-d3 Chemical Structure
  25. GC44801 R-(-)-Flecainide R-(-)-Flecainide is the (R) enantiomer of the antiarrhythmic agent flecainide. R-(-)-Flecainide Chemical Structure
  26. GC44803 rac-7-hydroxy Propranolol (hydrochloride) rac-7-hydroxy Propranolol (hydrochloride) is a ring-hydroxylated isomer and metabolite of propranolol that is an antagonist at β-adrenergic receptors (0.95 potency relative to propranolol). rac-7-hydroxy Propranolol (hydrochloride) Chemical Structure
  27. GC40967 rac-7-methoxy Propranolol Propranolol, one of the first β-blockers used in cardiovascular medicine, inhibits β1-, β2-, and β3-adrenergic receptors with log KD values of -8.16, -9.08, and -6.93, respectively. rac-7-methoxy Propranolol Chemical Structure
  28. GC49291 rac-N-desmethyl Ivabradine-d6 (hydrochloride) An internal standard for the quantification of N-desmethyl ivabradine rac-N-desmethyl Ivabradine-d6 (hydrochloride) Chemical Structure
  29. GC49108 Racecadotril-d5 An internal standard for the quantification of racecadotril Racecadotril-d5 Chemical Structure
  30. GC49653 Ramipril Diketopiperazine A potential impurity found in commercial preparations of ramipril Ramipril Diketopiperazine Chemical Structure
  31. GC49408 Ramipril Diketopiperazine Acid A potential impurity found in commercial preparations of ramipril Ramipril Diketopiperazine Acid Chemical Structure
  32. GC40234 Ramipril-d5 Ramipril-d5 is intended for use as an internal standard for the quantification of ramipril by GC- or LC-MS. Ramipril-d5 Chemical Structure
  33. GC40235 Ranolazine-d5 Ranolazine-d5 is intended for use as an internal standard for the quantification of ranolazine by GC- or LC-MS. Ranolazine-d5 Chemical Structure
  34. GC48972 Resolvin E2 A specialized pro-resolving mediator Resolvin E2 Chemical Structure
  35. GC48052 Rilmenidine-d4 An internal standard for the quantification of rilmenidine Rilmenidine-d4 Chemical Structure
  36. GC60326 Rivaroxaban D4 An internal standard for the quantification of rivaroxaban Rivaroxaban D4 Chemical Structure
  37. GC49413 Rizatriptan N-oxide A potential impurity found in commercial preparations of rizatriptan Rizatriptan N-oxide Chemical Structure
  38. GC48583 Rizatriptan-d6 (benzoate salt) An internal standard for the quantification of rizatriptan Rizatriptan-d6 (benzoate salt) Chemical Structure
  39. GC49107 Rosuvastatin lactone The lactone form of rosuvastatin Rosuvastatin lactone Chemical Structure
  40. GC48060 Rosuvastatin-d6 (sodium salt) An internal standard for the quantification of rosuvastatin Rosuvastatin-d6 (sodium salt) Chemical Structure
  41. GC49190 Roxadustat-d5 An internal standard for the quantification of roxadustat Roxadustat-d5 Chemical Structure
  42. GC44860 S1QEL1.1 S1QEL1.1 is a small molecule that suppresses superoxide production during reverse electron transport through the IQ site of the mitochondrial respiratory complex I (IC50 = 70 nM) without affecting oxidative phosphorylation. S1QEL1.1 Chemical Structure
  43. GC49093 Safflower Red A red pigment with diverse biological activities Safflower Red Chemical Structure
  44. GC44868 Salbutamol (hydrochloride) Levalbuterol ((R)-Albuterol) hydrochloride is a short-acting β2-adrenergic receptor agonist and the active (R)-enantiomer of Salbutamol. Salbutamol (hydrochloride) Chemical Structure
  45. GC45558 Salbutamol-d9   Salbutamol-d9 Chemical Structure
  46. GC49679 Sauvagine (trifluoroacetate salt) A neuropeptide hormone Sauvagine (trifluoroacetate salt) Chemical Structure
  47. GC49333 SH-42 An inhibitor of DHCR24 SH-42 Chemical Structure
  48. GC49358 Sildenafil Chlorosulfonyl An intermediate in the synthesis of sildenafil Sildenafil Chlorosulfonyl Chemical Structure
  49. GC48078 Sildenafil-d3 An internal standard for the quantification of sildenafil Sildenafil-d3 Chemical Structure
  50. GC50196 Simvastatin - d6 Deuterated simvastatin Simvastatin - d6 Chemical Structure
  51. GC49002 Sinigrin (hydrate) A glucosinolate with diverse biological activities Sinigrin (hydrate) Chemical Structure
  52. GC44910 Sodium Hydrogen Sulfide (hydrate) Hydrogen sulfide (H2S) is, like nitric oxide, an important gaseous mediator that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals. Sodium Hydrogen Sulfide (hydrate) Chemical Structure
  53. GC49341 Spermidine-d6 An internal standard for the quantification of spermidine Spermidine-d6 Chemical Structure
  54. GC52390 Spexin 1 (human, mouse, rat, bovine) (acetate) An endogenous peptide and agonist of GAL2 and GAL3 Spexin 1 (human, mouse, rat, bovine) (acetate) Chemical Structure
  55. GC52233 SSPalmO-Phe An ionizable cationic self-degradable SSPalm SSPalmO-Phe Chemical Structure
  56. GC52011 Stearic Acid glycidyl ester An esterified form of stearic acid Stearic Acid glycidyl ester Chemical Structure
  57. GC49770 Stearic Acid glycidyl ester-d5 An internal standard for the quantification of stearic acid glycidyl ester Stearic Acid glycidyl ester-d5 Chemical Structure
  58. GC52112 Stercobilinogen (technical grade) A metabolite of bilirubin and a precursor in the biosynthesis of stercobilin Stercobilinogen (technical grade) Chemical Structure
  59. GC49500 Stobadine A pyridoindole antioxidant Stobadine Chemical Structure
  60. GC48117 Sumatriptan-d6 (succinate) An internal standard for the quantification of sumatriptan Sumatriptan-d6 (succinate) Chemical Structure
  61. GC52125 T-1095 T-1095 is a selective and orally active Na+-glucose cotransporter (SGLT) inhibitor with IC50s of 22.8 ?M and 2.3 ?M for human SGLT1 and SGLT2, respectively. T-1095 Chemical Structure
  62. GC48121 Tadalafil-d3 An internal standard for the quantification of tadalafil Tadalafil-d3 Chemical Structure
  63. GC52460 tcY-NH2 (trifluoroacetate salt) A peptide antagonist of PAR4 tcY-NH2 (trifluoroacetate salt) Chemical Structure
  64. GC45007 Telmisartan Acyl-β-D-Glucuronide Telmisartan acyl-β-D-glucuronide is a major metabolite of the angiotensin II receptor antagonist telmisartan. Telmisartan Acyl-β-D-Glucuronide Chemical Structure
  65. GC52478 Telmisartan Acyl-β-D-Glucuronide (hydrate) A major metabolite of telmisartan Telmisartan Acyl-β-D-Glucuronide (hydrate) Chemical Structure
  66. GC48137 Telmisartan-d3 An internal standard for the quantification of telmisartan Telmisartan-d3 Chemical Structure
  67. GC18202 Temocaprilat An ACE inhibitor Temocaprilat Chemical Structure
  68. GC49386 Tepoxalin A dual inhibitor of COX and 5-LO Tepoxalin Chemical Structure
  69. GC45017 Terpendole C Terpendole C is an indole diterpene alkaloid fungal metabolite originally isolated from A. Terpendole C Chemical Structure
  70. GC48162 Theobromine-d6 An internal standard for the quantification of theobromine Theobromine-d6 Chemical Structure
  71. GC48174 Thiorphan-d5 An internal standard for the quantification of thiorphan Thiorphan-d5 Chemical Structure
  72. GP10085 Thrombin Receptor Activator for Peptide 5 (TRAP-5) Thrombin Receptor Activator for Peptide 5 (TRAP-5) Chemical Structure
  73. GC45050 Thrombin Receptor Agonist Peptide (trifluoroacetate salt) Thrombin receptor agonist peptide (TRAP-14) is a 14-amino acid peptide agonist of the α-thrombin receptor. Thrombin Receptor Agonist Peptide (trifluoroacetate salt) Chemical Structure
  74. GC45051 Thrombin Receptor Peptide Ligand (trifluoroacetate salt) Thrombin receptor peptide ligand is antagonist of the thrombin receptor (EC50s = 16-33 μM to inhibit platelet aggregation in vitro). Thrombin Receptor Peptide Ligand (trifluoroacetate salt) Chemical Structure
  75. GC52254 Thrombin-Sensitive Peptide (ammonium acetate salt) A synthetic peptide containing a thrombin-releasable quencher Thrombin-Sensitive Peptide (ammonium acetate salt) Chemical Structure
  76. GC48180 Ticagrelor-d7 An internal standard for the quantification of ticagrelor Ticagrelor-d7 Chemical Structure
  77. GC49076 Tilmicosin-d3 An internal standard for the quantification of tilmicosin Tilmicosin-d3 Chemical Structure
  78. GC49062 Tiopronin-d3 An internal standard for the quantification of tiopronin Tiopronin-d3 Chemical Structure
  79. GC45057 TIQ-A Poly(ADP-ribose) polymerase 1 (PARP1) is a critical DNA repair enzyme involved in DNA single-strand break repair via the base excision repair pathway. TIQ-A Chemical Structure
  80. GC19438 TMB 8 (hydrochloride) TMB 8 is a non-competitive antagonist of nicotinic acetylcholine receptors (nAChRs) with IC50 values of 390 and 350 nM, respectively, for human muscle-type and α3β4 subunit-containing ganglionic nAChRs expressed in TE671/RD or SH-SY5Y cells. TMB 8 (hydrochloride) Chemical Structure
  81. GC45060 TMP-153 Acyl-CoA:cholesterol acyltransferase (ACAT) catalyses the esterification of excess cellular cholesterol with fatty acids and is important for intestinal cholesterol absorption, hepatic lipoprotein secretion, and cholesterol accumulation in vascular tissues. TMP-153 Chemical Structure
  82. GC48186 Tolvaptan-d7 An internal standard for the quantification of tolvaptan Tolvaptan-d7 Chemical Structure
  83. GC48187 Torasemide-d7 An internal standard for the quantification of torasemide Torasemide-d7 Chemical Structure
  84. GC46233 Trandolaprilat (hydrate) Trandolaprilat (hydrate) is a potent angiotensin-converting enzyme (ACE) inhibitor. Trandolaprilat (hydrate) Chemical Structure
  85. GC52436 TRAP-6 amide (trifluoroacetate salt) A peptide PAR1 agonist TRAP-6 amide (trifluoroacetate salt) Chemical Structure
  86. GC45073 TRAP-6 Peptide (trifluoroacetate salt) TRAP-6 peptide is a hexapeptide corresponding to residues 42-47 of protease-activated receptor 1 (PAR1). TRAP-6 Peptide (trifluoroacetate salt) Chemical Structure
  87. GC48202 Treprostinil (diethanolamine salt) Treprostinil (UT-15C) diethanolamine is a potent EP2, DP1 and IP agonist with Ki values of 3.6, 4.4, 32.1, 212, 826, 2505 and 4680 nM for EP2, DP1, IP, EP1, EP4, EP3 and FP, respectively. Treprostinil (diethanolamine salt) Chemical Structure
  88. GC49141 Triacontanoic Acid A very long-chain saturated fatty acid Triacontanoic Acid Chemical Structure
  89. GC52005 Triazolomethylindole-3-acetic Acid A metabolite of rizatriptan Triazolomethylindole-3-acetic Acid Chemical Structure
  90. GC49072 Tribenoside A vasoprotective agent Tribenoside Chemical Structure
  91. GC49884 Trigonelline-d3 (chloride) An internal standard for the quantification of trigonelline Trigonelline-d3 (chloride) Chemical Structure
  92. GC48206 Trimethylamine-d9 N-oxide An internal standard for the quantification of trimethylamine N-oxide Trimethylamine-d9 N-oxide Chemical Structure
  93. GC45090 Triparanol Triparanol is a 24-dehydro cholesterol reductase (DHCR24) inhibitor (Ki = 0.523 μM), which is an enzyme involved in the biosynthesis of cholesterol. Triparanol Chemical Structure
  94. GC49389 Tritylolmesartan Medoxomil An intermediate in the synthesis of olmesartan medoxomil Tritylolmesartan Medoxomil Chemical Structure
  95. GC45096 Tyr-α-CGRP (human) (trifluoroacetate salt) Tyr-α-CGRP is an N-terminal extended tyrosinated analogue of α-calcitonin gene-related peptide. Tyr-α-CGRP (human) (trifluoroacetate salt) Chemical Structure
  96. GC18962 U-92016A U-92016A is a potent, metabolically stable, orally acitive 5-HT1A receptor agonist with an exceptionally high degree of intrinsic activity. U-92016A Chemical Structure
  97. GC49328 UDP-α-D-Galactose (sodium salt) A nucleotide sugar UDP-α-D-Galactose (sodium salt) Chemical Structure
  98. GC45126 Uric Acid (sodium salt) Uric Acid (sodium salt) (Monosodium urate), scavenger of oxygen radical, is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. Uric Acid (sodium salt) Chemical Structure
  99. GC49812 Urobilin (hydrochloride) A byproduct of hemoglobin degradation Urobilin (hydrochloride) Chemical Structure
  100. GC18231 Urocortin II (human) (trifluoroacetate salt) Urocortin II is a neuropeptide hormone and member of the corticotropin-releasing factor (CRF) family which includes mammalian CRF , urocortin , urocortin III , frog sauvagine, and piscine urotensin I. Urocortin II (human) (trifluoroacetate salt) Chemical Structure
  101. GC45130 Urodilatin Urodilatin is a renal natriuretic peptide first isolated from human urine. Urodilatin Chemical Structure

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