CRTH2
CRTh2 (chemoattractant receptor homologous molecule expressed on T-Helper type 2 cells ) is a G-protein coupled receptor for prostaglandin D2. Activation of CRTh2 increases the chemotaxis of Th2 cells/eosinophils/basophil, as well as eosinophil degranulation and Th2 cells cytokine release.
Products for CRTH2
- Cat.No. 상품명 정보
- GC12434 AZD1981 AZD1981은 강력하고 선택적인 CRTh2 길항제입니다. 높은 효능으로 인간 재조합 DP2에서 방사성 표지된 PGD2를 대체합니다(pIC50 = 8.4).
- GC13196 NVP-QAV680 potent and selective CRTh2 receptor antagonist