CRTH2
CRTh2 (chemoattractant receptor homologous molecule expressed on T-Helper type 2 cells ) is a G-protein coupled receptor for prostaglandin D2. Activation of CRTh2 increases the chemotaxis of Th2 cells/eosinophils/basophil, as well as eosinophil degranulation and Th2 cells cytokine release.
製品は CRTH2
- Cat.No. 商品名 インフォメーション
- GC12434 AZD1981 AZD1981 は、強力で選択的な CRTh2 拮抗薬です。ヒト組換え DP2 から放射性標識 PGD2 を高い効力で置換します (pIC50 = 8.4)。
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GC13196
NVP-QAV680
強力かつ選択的なCRTh2受容体拮抗剤