Ro-0335 (Synonyms: VM 1500A) |
| Catalog No.GC62223 |
RO-0335는 새롭고 강력한 diphenylether nonnucleoside reverse transcriptase inhibitor(NNRTI)입니다. RO-0335는 1.1nM의 IC50으로 Wt HIV-1을 억제하고 많은 수의 NNRTI 내성 임상 분리주의 92%에 대해 활성(IC50<100nM)을 유지합니다.
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Cas No.: 867365-76-2
Sample solution is provided at 25 µL, 10mM.
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RO-0335 is a novel and potent diphenylether nonnucleoside reverse transcriptase inhibitor(NNRTI). RO-0335 inhibits Wt HIV-1 with an IC50 of 1.1 nM and retained activity (IC50< 100 nM) against 92% of a large number of NNRTI-resistant clinical isolates[1].
[1]. Javanbakht H, et al. In vitro resistance development for RO-0335, a novel diphenylether nonnucleoside reverse transcriptase inhibitor. Antiviral Res. 2010;86(2):212-219.
Average Rating: 5 (Based on Reviews and 22 reference(s) in Google Scholar.)
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