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Ro-0335 (Synonyms: VM 1500A)

カタログ番号GC62223

RO-0335 は、新規で強力なジフェニルエーテル非ヌクレオシド系逆転写酵素阻害剤 (NNRTI) です。 RO-0335 は、1.1 nM の IC50 で Wt HIV-1 を阻害し、多数の NNRTI 耐性臨床分離株の 92% に対して活性を保持します (IC50 < 100 nM)。

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Ro-0335 化学構造

Cas No.: 867365-76-2

サイズ 価格 在庫数 個数
5 mg
$135.00
在庫あり
10 mg
$225.00
在庫あり
25 mg
$495.00
在庫あり
50 mg
$855.00
在庫あり
100 mg
$1,395.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

RO-0335 is a novel and potent diphenylether nonnucleoside reverse transcriptase inhibitor(NNRTI). RO-0335 inhibits Wt HIV-1 with an IC50 of 1.1 nM and retained activity (IC50< 100 nM) against 92% of a large number of NNRTI-resistant clinical isolates[1].

[1]. Javanbakht H, et al. In vitro resistance development for RO-0335, a novel diphenylether nonnucleoside reverse transcriptase inhibitor. Antiviral Res. 2010;86(2):212-219.

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Average Rating: 5 ★★★★★ (Based on Reviews and 22 reference(s) in Google Scholar.)

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