Roquefortine C (Synonyms: NSC 292134) |
| Catalog No.GC18460 |
Penicillium roquefortii에서 분리된 곰팡이 cyclopeptide인 Roquefortine C는 P-gp를 활성화하고 P450-3A 및 기타 혈단백도 억제합니다.
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Cas No.: 58735-64-1
Sample solution is provided at 25 µL, 10mM.
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Roquefortine C is a mycotoxin that was first isolated from a strain of P. roqueforti, a species of Penicillium commercially used to ripen blue-veined cheeses. It has also been isolated from other members of the Penicillium genus found in contaminated food products where it displays neurotoxic properties. It has been shown to both activate a P-glycoprotein transport system involved in the efflux of xenobiotics and to inhibit cytochrome P450 3A detoxification enzymes. It has also been used as a biomarker for penitrem A intoxication.
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Average Rating: 5 (Based on Reviews and 15 reference(s) in Google Scholar.)
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