Roquefortine C (Synonyms: NSC 292134) |
| カタログ番号GC18460 |
Penicillium roquefortii から分離された菌類シクロペプチドである Roquefortine C は、P-gp を活性化し、P450-3A および他のヘモプロテインも阻害します。
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Cas No.: 58735-64-1
Sample solution is provided at 25 µL, 10mM.
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Roquefortine C is a mycotoxin that was first isolated from a strain of P. roqueforti, a species of Penicillium commercially used to ripen blue-veined cheeses. It has also been isolated from other members of the Penicillium genus found in contaminated food products where it displays neurotoxic properties. It has been shown to both activate a P-glycoprotein transport system involved in the efflux of xenobiotics and to inhibit cytochrome P450 3A detoxification enzymes. It has also been used as a biomarker for penitrem A intoxication.
Review for Roquefortine C
Average Rating: 5 (Based on Reviews and 15 reference(s) in Google Scholar.)
Review for Roquefortine C
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