Sultopride hydrochloride (LIN-1418 hydrochloride) |
| Catalog No.GC30944 |
Sultopride hydrochloride (LIN-1418 hydrochloride) (LIN-1418 hydrochloride)는 도파민 D2 수용체의 선택적 길항제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 23694-17-9
Sample solution is provided at 25 µL, 10mM.
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Sultopride hydrochloride is a selective antagonist of dopamine D2 receptor.
Sultopride hydrochloride is a selective antagonist of dopamine D2 receptor. DOPAC and HVA levels in the striatum, the nucleus accumbens and the medial prefrontal cortex are higher in the rats treated with Sultopride hydrochloride and sulpiride than those of the controls. In the striatum, DOPAC and HVA levels are higher in the Sultopride hydrochloride-treated rats than the sulpiride-treated rats (p<0.05). In the nucleus accumbens, DOPAC levels are higher in the Sultopride hydrochloride-treated rats than sulpiride treated rats (p<0.05). In the Sultopride hydrochloride-treated rats, DOPAC and HVA levels are higher in the striatum or in the nucleus accumbens than in the medial prefrontal cortex (p<0.05)[1].
[1]. Moriuchi K, et al. Differences in effects of sultopride and sulpiride on dopamine turnover in rat brain. Neurochem Res. 1995 Jan;20(1):95-9.
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