Sultriecin (Synonyms: BU-3285T, Phostriecin) |
| Catalog No.GC44973 |
Sultriecin은 Streptomyces pulveraceus가 생산하는 항종양 항생제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 131774-59-9
Sample solution is provided at 25 µL, 10mM.
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Sultriecin is a fungal metabolite originally isolated from S. roseiscleroticus. It is active against a panel of 15 fungal strains (MICs = 0.8-50 μg/ml). Sultriecin is cytotoxic to B16/F10, HCT116, Moser, P388, A549, and K562 cancer cells (IC50s = 37.7, 1.92, 0.85, 3.8, 4.14, and 0.67 μg/ml, respectively). It also inhibits RNA and protein synthesis in L1210 leukemia cells (IC50s = 5.5 and 2.4 μg/ml, respectively). Sultriecin (0.1-10 mg/kg) increases survival time in a B16/F10 syngeneic mouse melanoma model and a P388 murine leukemia model.
Average Rating: 5 (Based on Reviews and 13 reference(s) in Google Scholar.)
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